Status:

COMPLETED

Quetiapine Fumarate Bipolar Maintenance Monotherapy

Lead Sponsor:

AstraZeneca

Conditions:

Bipolar Disorder

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This is a multicenter, randomized, parallel-group, double-blind, placebo-controlled study to evaluate the efficacy and safety of quetiapine and lithium (comparator in the study) for up to 104 weeks of...

Eligibility Criteria

Inclusion

  • Signed informed consent
  • 18 years or older
  • A diagnosis of Bipolar I Disorder
  • Have a current manic, depressed or mixed episode
  • Have had a manic, depressed or mixed episode during the last 26 weeks that was treated with quetiapine
  • Female patients of childbearing potential must be using a reliable method of contraception

Exclusion

  • Pregnancy
  • Substance or alcohol dependence at enrollment
  • Unstable thyroid function
  • Unstable Diabetes
  • Unstable or inadequately treated medical illness e.g., angina pectoris and hypertension
  • Use of an experimental drug within 30 days of enrollment

Key Trial Info

Start Date :

March 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2007

Estimated Enrollment :

1255 Patients enrolled

Trial Details

Trial ID

NCT00314184

Start Date

March 1 2005

End Date

July 1 2007

Last Update

December 22 2008

Active Locations (95)

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Page 1 of 24 (95 locations)

1

Research Site

Cerritos, California, United States

2

Research Site

San Diego, California, United States

3

Research Site

Santa Ana, California, United States

4

Research Site

Washington D.C., District of Columbia, United States