Status:
COMPLETED
The Effects of Cranberry Juice on Bacterial Adhesion
Lead Sponsor:
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Collaborating Sponsors:
Otsuka Pharmaceutical Co., Ltd.
Conditions:
Bacterial Vaginosis
Oxaluria
Eligibility:
FEMALE
19-45 years
Phase:
NA
Brief Summary
The study is based on the hypothesis that consumption of cranberry juice products results in the production of metabolites in the urine that have anti-adhesive properties on bacteria. A crossover stud...
Detailed Description
Hypothesis: Metabolites in cranberry juice, have anti-adhesive properties for uropathogenic bacteria but they do not disturb the normal vaginal flora. Study design and assays: A crossover study desi...
Eligibility Criteria
Inclusion
- Age 19-45 years
- Healthy pre-menopausal female volunteers with no history of urinary tract infections over the past 12 months.
Exclusion
- Experienced a urinary tract infection in the past 12 months
- Receiving antibiotic therapy or supplements to prevent urinary tract infections
- Pregnant, postmenopausal or outside of the age range (19-45 years old)
- Anatomical abnormality of the urinary tract, such as following surgery
- Using a catheter to manage micturition
- Diabetic
- Allergic to berry juices
Key Trial Info
Start Date :
March 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2006
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00318253
Start Date
March 1 2006
End Date
August 1 2006
Last Update
July 9 2009
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