Status:

COMPLETED

Evaluation of Pre-dose and Post-dose Anti-factor Xa Levels With Enoxaparin Use During Pregnancy

Lead Sponsor:

University of California, Irvine

Collaborating Sponsors:

Long Beach Memorial Medical Center

Conditions:

Pregnancy

Eligibility:

FEMALE

18-45 years

Brief Summary

Venous thromboembolism is a condition that causes formation of blood clots in the body. It may have life threatening consequences if the leg veins, lungs or the brain blood vessels are involved. In pr...

Detailed Description

Study Design This is a prospective, non-blinded, pilot study of gravid patients receiving treatment doses of enoxaparin therapy. Subjects Subjects will include pregnant women at all gestational ages ...

Eligibility Criteria

Inclusion

  • Nulliparous or multiparous women with intrauterine pregnancies who are receiving twice daily treatment doses of enoxaparin (1 mg/kg ± 20% SC BID).
  • Subjects who consent to the study.

Exclusion

  • Women who are not pregnant.
  • Women who are receiving enoxaparin at prophylactic doses (i.e., 30 mg twice daily or 40 mg daily).
  • Women who are currently receiving another LMWH or UFH.
  • Women who are receiving other concomitant anticoagulant medications, such as warfarin, lepirudin, or argatroban.
  • Subjects who are unable or unwilling to give informed consent.
  • Women who, in the judgment of the investigators, would not be in the best interest of the patient to participate in the study.

Key Trial Info

Start Date :

April 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2007

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT00319176

Start Date

April 1 2004

End Date

December 1 2007

Last Update

February 8 2013

Active Locations (1)

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Long Beach Memorial Medical Center

Long Beach, California, United States, 90806