Status:

COMPLETED

Role of Antioxidants Supplementation in Chronic Pancreatitis

Lead Sponsor:

All India Institute of Medical Sciences

Conditions:

Chronic Pancreatitis

Eligibility:

All Genders

12-70 years

Phase:

PHASE3

Brief Summary

Chronic pancreatitis is a progressive inflammatory disease of the pancreas that presents with abdominal pain and in late stages may cause diabetes and malnutrition. The pain may be incapacitating and ...

Detailed Description

INTRODUCTION Chronic pancreatitis (CP) is a progressive inflammatory disease of the pancreas accompanied by abdominal pain and in late stages, by exocrine and endocrine insufficiency. The etiology of ...

Eligibility Criteria

Inclusion

  • CP with significant pain i.e., at least one episode of pain in a month requiring oral analgesic or one episode of severe pain in last three months requiring hospitalization

Exclusion

  • Painless disease
  • Current pain more likely due to non-pancreatic origin
  • If the patient already has an intervention in the form decompressive therapy i.e., surgery or endoscopic sphincterotomy/ stenting or ESWL
  • Systemic conditions like CRF, malignancy, hypertension, and pregnancy
  • Complications like pseudocyst, pancreatic abscess
  • Patients who would have received antioxidants in the preceding 4 weeks
  • Narcotic addicts
  • Uncontrolled diabetes
  • Comorbid conditions like liver diseases

Key Trial Info

Start Date :

October 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2006

Estimated Enrollment :

127 Patients enrolled

Trial Details

Trial ID

NCT00319358

Start Date

October 1 2003

End Date

October 1 2006

Last Update

January 29 2009

Active Locations (1)

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1

A.I.I.M.S.

New Delhi, National Capital Territory of Delhi, India, 110029