Status:

COMPLETED

A Study to Evaluate the Effect of Vitamin D Supplementation on Insulin Sensitivity and Secretion

Lead Sponsor:

Sitaram Bhartia Institute of Science and Research

Conditions:

Diabetes Mellitus, Non-Insulin-Dependent

Eligibility:

MALE

30+ years

Phase:

NA

Brief Summary

The purpose of the study is to evaluate the change in insulin sensitivity and secretion indices (early markers for development of diabetes) after 4 weeks of a megadose of Vitamin D. This will also hel...

Detailed Description

Accumulating evidence suggests that serum Vitamin D levels may be inversely related to the prevalence of diabetes, to the concentration of glucose , insulin resistance and metabolic syndrome.The avail...

Eligibility Criteria

Inclusion

  • Male
  • ≥30 years of age
  • Waist circumference ≥80 cm

Exclusion

  • Diabetic- Fasting Blood Sugar \>126 mg/dl or on anti-diabetic medication
  • BP\>140/90 or on anti-hypertensive medication
  • Receiving Vitamin D or calcium supplementation
  • Chronic disease-renal/hepatic/malignancy/gastrointestinal
  • On any medication within the last one month which could potentially influence insulin secretion, insulin sensitivity, Vitamin D or Calcium metabolism
  • Febrile illness or infective morbidity in the past 10 days

Key Trial Info

Start Date :

April 1 2006

Trial Type :

INTERVENTIONAL

End Date :

May 1 2006

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00320853

Start Date

April 1 2006

End Date

May 1 2006

Last Update

May 3 2006

Active Locations (1)

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Sitaram Bhartia Institute of Science and Research

New Delhi, National Capital Territory of Delhi, India, 110016