Status:

COMPLETED

Study of a Booster Dose of Hib-MenC Conjugate Vaccine vs Infanrix Hexa When Given to 14 Month Old Subjects

Lead Sponsor:

GlaxoSmithKline

Conditions:

Neisseria Meningitidis

Haemophilus Influenzae Type b

Eligibility:

All Genders

13-14 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the immunogenicity, safety and reactogenicity of a booster dose of the Hib-MenC conjugate vaccine when given to healthy subjects aged 13 to 14 months who were ...

Detailed Description

The study is open and Infanrix hexa will serve as active control. Subjects will receive one vaccine dose of either Hib-MenC or Infanrix hexa, and will have 2 blood samples taken: before and one month ...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Healthy male or female between, and including, 13 and 14 months of age
  • Having participated in the primary vaccination study 217744/097.
  • Exclusion criteria:
  • Previous vaccination against OR history of OR known exposure to diphtheria, tetanus, pertussis, hepatitis B, polio, H. influenzae type b (Hib) and/or meningococcal serogroup C disease except if within the framework of study 217744/097
  • Any confirmed or suspected immunosuppressive or immunodeficient condition, including human immunodeficiency virus (HIV) infection
  • A family history of congenital or hereditary immunodeficiency
  • History of any neurologic disorders or seizures

Exclusion

    Key Trial Info

    Start Date :

    November 1 2004

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2005

    Estimated Enrollment :

    468 Patients enrolled

    Trial Details

    Trial ID

    NCT00323050

    Start Date

    November 1 2004

    End Date

    March 1 2005

    Last Update

    September 16 2016

    Active Locations (16)

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    Page 1 of 4 (16 locations)

    1

    GSK Investigational Site

    Alcorcón, Spain, 28922

    2

    GSK Investigational Site

    Almeira, Spain, 4009

    3

    GSK Investigational Site

    Barcelona, Spain, 08025

    4

    GSK Investigational Site

    Barcelona, Spain, 08950