Status:

COMPLETED

A Phase II Trial Comparing the Quality of Life, Tolerability and Toxicity of PEG Intron With INTRON® A in Patients With Multiple Myeloma

Lead Sponsor:

Royal Marsden NHS Foundation Trust

Conditions:

Multiple Myeloma

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Multiple myeloma is a rare form of malignancy in which neoplastic plasma cells accumulate in the bone marrow. Most malignant plasma cells continue to produce immunoglobulin. The activity of multiple m...

Eligibility Criteria

Inclusion

  • Patients  18 years of age with a definite diagnosis of multiple myeloma.
  • Patients have been on a steady dose of INTRON®A for at least 6 weeks and have tolerated it (randomized study only), or patients who within six weeks of starting INTRON®A become intolerant (tolerability sub-study only)
  • Informed consent obtained

Exclusion

  • \- a) Patients with refractory Multiple Myeloma. b) Treatment with any investigational drug within 30 days of entry to this protocol.
  • c) Subjects who are pregnant, nursing, or of reproductive potential and who are not practising an effective means of contraception.

Key Trial Info

Start Date :

March 1 2001

Trial Type :

INTERVENTIONAL

End Date :

December 1 2004

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00323505

Start Date

March 1 2001

End Date

December 1 2004

Last Update

May 9 2006

Active Locations (1)

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1

Royal Marsden NHS trust

Sutton, Surrey, United Kingdom, SM2 5PT