Status:
COMPLETED
TMS for the Treatment of Pancreatic Cancer Pain
Lead Sponsor:
Beth Israel Deaconess Medical Center
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Pain
Visceral Pain
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This is a phase II study that aims to investigate prospectively a new therapy for a cohort of patients with chronic pain attributed to pancreatic cancer. The justification of this study is that the pa...
Detailed Description
The primary aim of this protocol is to investigate a possible novel treatment for visceral pain in patients with locally advanced or advanced pancreatic cancer. Pain is a major contributor to the poor...
Eligibility Criteria
Inclusion
- Locally advanced or metastatic pancreatic cancer
- Abdominal pain attributable to pancreatic cancer that requires daily narcotic use
- Stable narcotic dosage the week before study entry
- A computed tomography of the abdomen within four weeks of study entry
- CA19-9 within four weeks of study entry
- ECOG Performance status \>=3
Exclusion
- Known brain metastasis
- Patients with major depression with suicidal risk
- Prior neurosurgical procedures
- History of epilepsy
- Previous head injury
- History of Stroke
- Abnormal neurological examination other than as signs of the condition studied in the present protocol
- Contraindication to TMS:
- Implanted pacemaker;Medication pump;Vagal stimulator;Deep brain stimulator;Metallic hardware in the head or scalp: shrapnel, surgical clips, or fragments from welding;Signs of increased intracranial pressure
- TENS unit and ventriculo-peritoneal shunt
- Pregnancy
- Unable to undergo a brain MR
- claustrophobia refractory to anxiolytics
- ferromagnetic metal in the body such as a prosthetic heart valve, a pacemaker, or a brain aneurysm clip).
Key Trial Info
Start Date :
May 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2011
Estimated Enrollment :
3 Patients enrolled
Trial Details
Trial ID
NCT00324428
Start Date
May 1 2006
End Date
November 1 2011
Last Update
March 21 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States, 02215