Status:

COMPLETED

Prevention Allergic Disease of Infant With Probiotics During Pregnancy and Neonatal Period

Lead Sponsor:

Chang Gung Memorial Hospital

Conditions:

Atopic Dermatitis

Allergic Rhinitis

Eligibility:

FEMALE

Phase:

PHASE3

Brief Summary

The purpose of this study is to determine whether childhood atopic disease decrease or not after allowing allergic mothers intake of probiotic (Lactobacillus GG) in second trimester, followed by infan...

Detailed Description

The prevalence of atopy at Taiwan increased 8 times in past 20 years and also increased all over the world. In our previous study, maternal atopic history rather than paternal one is the major factor ...

Eligibility Criteria

Inclusion

  • Pregnant women with atopic disease, which was determined with atopic history, elevated total IgE \> 100 kU/l and positive specific IgE

Exclusion

  • Multiple pregnancy

Key Trial Info

Start Date :

April 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2010

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT00325273

Start Date

April 1 2005

End Date

April 1 2010

Last Update

March 17 2015

Active Locations (1)

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Kaohsiung Chang Gung Memorial Hospital

Kaohsiung City, Niao-Sung, Taiwan, 833