Status:
COMPLETED
A Neurocognitive Model of Anorexia Nervosa
Lead Sponsor:
New York State Psychiatric Institute
Collaborating Sponsors:
Klarman Family Foundation
National Institute of Mental Health (NIMH)
Conditions:
Anorexia Nervosa
Eligibility:
All Genders
16-45 years
Brief Summary
The purpose of this study is to investigate thought processes and neural mechanisms that may contribute to the development of habitual behaviors. The investigators hypothesize that patients with AN wi...
Detailed Description
Patients with Anorexia Nervosa (AN) have extreme difficulty changing their eating behavior, even when they express desire for change. These behaviors seem to override all other potential responses, an...
Eligibility Criteria
Inclusion
- Inclusion:
- DSM-IV-TR™ diagnosis of anorexia nervosa (restricting or binge-purge subtype), current or prior;
- Age 16-45;
- Inpatient on GCRU
- Medically stable.
- Exclusion:
- Any other current major Axis I disorder (including current bulimia nervosa), except major depression;
- History of concussion, seizure disorder, or other neurological illness;
- History of learning disability;
- Acute Suicidality
- Healthy comparison group:
- Inclusion:
- No current or past psychiatric illness;
- Age 16-45
- No history of binge eating or vomiting;
- Normal weight (80%-120% ideal body weight)
- Exclusion:
- Significant medical or neurologic illness(concussion, seizure disorder, learning disability, other neurological illness)
- Current psychotropic medication or medications known to impact cognition
- Additional Exclusion Criteria for fMRI:
- Significant Claustrophobia
- Pregnancy
- Indwelling metallic object, non-removable metal jewelry, medicinal patch or recent metallic ink tattoo
- For patients, current psychotropic medications (antidepressants for 2 week (prozac and antipsychotics for 4 weeks)
- For patients, any other current Axis I diagnosis
Exclusion
Key Trial Info
Start Date :
May 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT00325520
Start Date
May 1 2006
End Date
May 1 2014
Last Update
August 15 2014
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.