Status:

COMPLETED

De Novo Sirolimus-based Immunosuppression After Liver Transplantation for Hepatocellular Carcinoma

Lead Sponsor:

University of Alberta

Conditions:

Liver Carcinoma

Eligibility:

All Genders

18-70 years

Phase:

PHASE2

PHASE3

Brief Summary

This study investigates whether sirolimus could decrease the rate of hepatoma recurrence after liver transplantation in high risk hepatoma patients.

Detailed Description

A total of 70 patients with HCC (mean age: 54.6 years, female/male: 12/58) received a liver transplant and were included in the study. Immunosuppression included de novo sirolimus, low-dose calcineuri...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Adult patients with hepatocellular (HCC) carcinoma receiving liver transplant
  • Exclusion criteria:
  • Patients less than 18 years of age

Exclusion

    Key Trial Info

    Start Date :

    December 1 1996

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2006

    Estimated Enrollment :

    70 Patients enrolled

    Trial Details

    Trial ID

    NCT00328770

    Start Date

    December 1 1996

    End Date

    March 1 2006

    Last Update

    June 24 2013

    Active Locations (1)

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    1

    University of Alberta

    Edmonton, Alberta, Canada, T6G 2B7