Status:

WITHDRAWN

Protocol for Postmenopausal Women at Increased Risk of Developing Breast Cancer

Lead Sponsor:

Carol Fabian, MD

Collaborating Sponsors:

Intergenetics, Inc.

Conditions:

Breast Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

A study to examine the potential associations between common single nucleotide polymorphisms and pre-cancerous conditions in breast tissue specimens from postmenopausal women.

Detailed Description

A study to examine the correlation between single nucleotide polymorphisms (SNPs) affecting steroid and carcinogen metabolism and benign breast tissue cytomorphology collected via random periareolar f...

Eligibility Criteria

Inclusion

  • postmenopausal women on or off hormone replacement therapy
  • at high risk of developing breast cancer determined by family or personal history
  • postmenopausal women not on hormone replacement therapy for at minimum six months prior to corresponding aspiration
  • willing to participate in companion protocol (KUMC HSC#4601) for random periareolar fine needle aspiration (RPFNA) for correlational studies

Exclusion

  • women who have been on raloxifene, tamoxifen, letrozole, anastrozole or exemestane within the six months prior to RPFNA.

Key Trial Info

Start Date :

May 1 2005

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 12 2015

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00329017

Start Date

May 1 2005

End Date

November 12 2015

Last Update

October 10 2019

Active Locations (1)

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1

University of Kansas Medical Center

Kansas City, Kansas, United States, 66160