Status:
COMPLETED
Study of the Influence of Vaccination in HIV Viral Load and Immunologic Responses Against HIV
Lead Sponsor:
Hospital Clinic of Barcelona
Conditions:
HIV
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether an immunization schedule is beneficial to HIV-infected patients with CD4 recount over 500 cells/mm3 and undetectable viral load.
Detailed Description
As HIV-infected patients are considered immunocompromised, it is generally recommended that they have to receipt appropriate vaccines. However data are conflicting concerning potential harmful effects...
Eligibility Criteria
Inclusion
- Age \>18 years
- Asymptomatic HIV infection
- CD4\>500/mm3 \>6 months prior to inclusion
- CD4 nadir \>300/mm3
- Being under HAART \> 1 year prior to inclusion
- Viral load\<200 copies/mL \> 6 months prior to inclusion
- Viral load previous to treatment \>5000 copies/mL
- Informed consent
Exclusion
- Pregnant women
- Basal creatinine \>2.5 mg/dL
- Allergy to either a vaccine or a ingredient of it
- Chronic hepatitis B
- GOT/GPT \> 250 IU/L
Key Trial Info
Start Date :
April 1 2003
Trial Type :
INTERVENTIONAL
End Date :
March 1 2006
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT00329251
Start Date
April 1 2003
End Date
March 1 2006
Last Update
May 24 2006
Active Locations (1)
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1
Department of Infectious Diseases, Hospital Clínic, C/Villarroel 170
Barcelona, Barcelona, Spain, 08036