Status:

COMPLETED

Efficacy of Re-treatment With Cimzia® in Subject With Chronic Plaque Psoriasis

Lead Sponsor:

UCB Pharma

Conditions:

Psoriasis

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The primary objective is to assess differences in PASI scores between Week 12 of Study C87040 \[NCT00245765\] and Week 12 of re-treatment in this study.

Eligibility Criteria

Inclusion

  • Subject having responded to treatment at Week 12 in study C87040 and having relapsed during the follow-up period
  • Female subjects either postmenopausal for at least one year, surgically incapable of childbearing, or effectively practising an acceptable method of contraception.Subjects agreed to continue using adequate contraception during the study and for 12 weeks after the last dose of CDP870

Exclusion

  • Subjects with erythrodermic, guttate, generalized pustular form of psoriasis
  • Any recent serious or life-threatening infection or any current sign or symptom that may indicate an infection (e.g., fever, cough)
  • Positive hepatitis B surface antigen test and /or hepatitis C antibody test results
  • Positive human immunodeficiency virus (HIV) test result
  • White blood cell counts less than 4000 per cubic millimeter or more than 20000 per cubic millimeter
  • Suspected or diagnosed demyelinating disease of the central nervous system (e.g. multiple sclerosis or optic neuritis)
  • Systemic Lupus Erythematosus
  • Participation in a clinical study within the past 3 months except Study C87040
  • Any other condition, which in the Investigator's judgment would make the subject unsuitable for inclusion in the study

Key Trial Info

Start Date :

April 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2007

Estimated Enrollment :

71 Patients enrolled

Trial Details

Trial ID

NCT00329303

Start Date

April 1 2006

End Date

May 1 2007

Last Update

May 6 2019

Active Locations (14)

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Page 1 of 4 (14 locations)

1

Besançon, France

2

Créteil, France

3

Nice, France

4

Paris, France