Status:
WITHDRAWN
A Comparison of Compliance Between Clonidine Patch and Methyldopa for the Treatment of Chronic Hypertension in Pregnancy
Lead Sponsor:
Afshan B. Hameed, M.D.
Conditions:
Hypertension
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
High blood pressure (BP) before pregnancy is called chronic hypertension (CHTN), and is associated with an increased risk of development of pregnancy related high BP called preeclampsia, preterm deliv...
Detailed Description
Purpose of the Study: The purpose of this of open-label randomized clinical trial is to compare clonidine patch (Catapres-TTS®) and orally administered methyldopa (Aldomet®) over a 4-week period for ...
Eligibility Criteria
Inclusion
- Intrauterine pregnancy between 14 - 28 weeks of gestation
- Chronic hypertension requiring antihypertensive therapy (BP \< 180/110)
- Subjects who consent to the study
- No evidence of fetal compromise (i.e. intrauterine growth restriction)
Exclusion
- Evidence or suspicion of preeclampsia
- Known cardiac disease
- Known renal dysfunction (creatinine \> 1 mg/dl)
- Known hepatic disease
- Known cerebrovascular disease
- Allergy to clonidine patch
Key Trial Info
Start Date :
September 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00329511
Start Date
September 1 2004
End Date
December 1 2008
Last Update
January 30 2018
Active Locations (1)
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1
Long Beach Memorial Medical Center
Long Beach, California, United States, 90806