Status:

COMPLETED

Using PET-CT to Target and Validate Low-frequency TMS as Treatment for Tinnitus

Lead Sponsor:

University of Arkansas

Collaborating Sponsors:

Tinnitus Research Consortium

Conditions:

Tinnitus

Eligibility:

All Genders

19-65 years

Phase:

NA

Brief Summary

One out of every five people experience tinnitus (a buzzing, ringing, or roaring sound in the ear) ranging from mild to severe impairment. To date there is no effective therapy that seems to help the ...

Detailed Description

Subjects will be up to 20 right-handed patients (men and women), 19-65 years of age, with debilitating unilateral or bilateral tinnitus. All subjects must report experiencing the presence of their pha...

Eligibility Criteria

Inclusion

  • right-handed subjects
  • 19-65 years of age
  • debilitating unilaterial or bilateral tinnitus
  • Experiencing the presence of phantom auditory preception for \>6 months
  • Tinnitus Handicap Questionnaire score of \>30

Exclusion

  • significant neurological disease
  • acoustic neuromas or glomus tumors
  • active Meniere's disease
  • profound hearing loss
  • non English speaking
  • personal or family history of epilepsy
  • personal history of head injury, aneurysm, stroke, previous cranial neurosurgery, neurological or psychiatric disorders, metal implants in the head or neck, a pacemaker, pregnancy, migraines,
  • medications that lower seizure threshold and are contraindicated
  • individuals who have been taking certain medications
  • claustrophobia
  • patients who do not exhibit significant cortical asymmetries on PET

Key Trial Info

Start Date :

June 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2008

Estimated Enrollment :

5 Patients enrolled

Trial Details

Trial ID

NCT00329524

Start Date

June 1 2006

End Date

August 1 2008

Last Update

May 4 2015

Active Locations (1)

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1

University of Arkansas for Medical Sciences

Little Rock, Arkansas, United States, 72205