Status:

COMPLETED

Double-Blind Naltrexone in Kleptomania

Lead Sponsor:

University of Minnesota

Conditions:

Kleptomania

Eligibility:

All Genders

21-75 years

Phase:

PHASE2

Brief Summary

The goal of the proposed study is to evaluate the efficacy and safety of naltrexone in kleptomania.

Detailed Description

The proposed study will consist of 8 weeks of treatment with either naltrexone or placebo in 20 subjects with kleptomania. The hypothesis to be tested is that naltrexone will be effective in reducing ...

Eligibility Criteria

Inclusion

  • men and women age 21-75
  • current DSM-IV kleptomania.

Exclusion

  • unstable medical illness or clinically significant abnormalities on prestudy laboratory tests or physical examination
  • history of seizures
  • myocardial infarction within 6 months
  • current pregnancy or lactation, or inadequate contraception in women of childbearing potential
  • clinically significant suicidality
  • current or recent (past 3 months) DSM-IV substance abuse or dependence
  • illegal substance within 2 weeks of study initiation
  • initiation of psychotherapy or behavior therapy from a mental health professional for the treatment of kleptomania within 3 months prior to study baseline
  • initiation of a psychotropic medication within 2 months prior to study inclusion
  • previous treatment with naltrexone
  • treatment with investigational medication or depot neuroleptics within 3 months, with fluoxetine within 6 weeks, or with other psychotropics within 2 weeks prior to study baseline.

Key Trial Info

Start Date :

May 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2008

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT00332579

Start Date

May 1 2006

End Date

September 1 2008

Last Update

July 29 2019

Active Locations (1)

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1

University of Minnesota

Minneapolis, Minnesota, United States, 55454