Status:
COMPLETED
Positive Effect of Ischemic Postconditioning During Acute Myocardial Infarction
Lead Sponsor:
French Cardiology Society
Conditions:
Acute Myocardial Infarction
Eligibility:
All Genders
18+ years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this study is to determine whether brief periods of ischemia performed just at the time of reperfusion -postconditioning- can reduce coronary endothelial dysfunction and infarct size in...
Detailed Description
Desobstruction of the culprit artery after acute myocardial infarction allows to reduce the consequences of prolonged ischemia. However, it is now clearly established that reperfusion induces by itsel...
Eligibility Criteria
Inclusion
- Acute myocardial infarction (\<6 hours)
- Occlusion of a major coronary vessel
Exclusion
- History of previous myocardial infarction
- History of Coronary Artery Bypass Grafting
- Need for Coronary Artery Bypass Grafting
- Stenosis not eligible for angioplasty
- Limited ischemic area
- Cardiogenic shock
- Interventricular septum rupture
- Mitral regurgitation\>2
- Ventricular tachycardia
- Atrioventricular block class II and III
Key Trial Info
Start Date :
September 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2011
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT00333320
Start Date
September 1 2006
End Date
November 1 2011
Last Update
October 23 2012
Active Locations (1)
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1
Henri Mondor University Hospital
Créteil, France, 94010