Status:

COMPLETED

Clinical Study on Optimised Removal of Protein-bound Uremic Toxins With Convective Dialysis Treatment.

Lead Sponsor:

University Hospital, Ghent

Collaborating Sponsors:

Gambro Corporate Research, Sweden

Conditions:

Chronic Renal Failure

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

Patients will be treated with hemodiafiltration (HDF) in postdilution mode, as a control therapy, during 9 weeks. During week 5 the 1st intervention treatment, predilution hemofiltration (HF) or predi...

Eligibility Criteria

Inclusion

  • stable on hemodialysis \>= 6 months
  • of which presently on high-flux HD \>= 1 month
  • 18 years \< age \< 85 years
  • blood flow rate \>= 300ml/min

Exclusion

  • expected survival \< 1 year
  • expected transplant within \< 1 year
  • infectious diseases
  • pregnancy
  • chronic inflammation condition
  • treated with single needle dialysis
  • presently treated with hemodiafiltration or low-flux hemodiafiltration
  • expected intradialytic body weight gain \>= 4kg

Key Trial Info

Start Date :

May 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2007

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT00337831

Start Date

May 1 2006

End Date

May 1 2007

Last Update

June 30 2011

Active Locations (1)

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1

University Hospital Ghent

Ghent, Belgium, 9000