Status:
COMPLETED
Exposure to Neurotoxins as Risk Factors for ALS
Lead Sponsor:
National Institute of Environmental Health Sciences (NIEHS)
Conditions:
ALS
Eligibility:
All Genders
Brief Summary
Chemicals called neurotoxins can harm the nervous system. Amyotrophic lateral sclerosis (ALS) is a progressive disease affecting movement. Researchers have studied many possible causes of ALS, includi...
Detailed Description
OBJECTIVES: Stored blood and toenail samples are available from a case-control study of ALS conducted in 1993-1996. The purpose of the initial study was to examine the relationship to ALS of lead and ...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Cases were eligible to participate in the original study if (1) they had received a diagnosis of ALS within 2 years; (2) they lived in New England at least half the year; (3) they spoke English; (4) they were mentally and physically able to participate. The same inclusion criteria were used for controls.
- EXCLUSION CRITERIA:
- Potential controls were excluded if they had a physician diagnosis of a neurodegenerative disease, polio, post-polio syndrome, or nondiabetic neuropathy.
- Pregnant women were excluded from both case and control groups.
Exclusion
Key Trial Info
Start Date :
June 3 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 23 2019
Estimated Enrollment :
397 Patients enrolled
Trial Details
Trial ID
NCT00340301
Start Date
June 3 2003
End Date
January 23 2019
Last Update
January 25 2019
Active Locations (1)
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1
New England Medical Center
Boston, Massachusetts, United States, 02111