Status:

COMPLETED

Analysis of NF2 Mutations in Radiation-Related Neural Tumors

Lead Sponsor:

National Cancer Institute (NCI)

Conditions:

Neural Tumors

Eligibility:

All Genders

Brief Summary

Adults treated with X-rays in childhood for benign conditions such as enlarged tonsils and adenoids have an increased risk of developing nervous system tumors. The risk is highest for schwannomas (RR ...

Detailed Description

Adults treated with X-rays in childhood for benign conditions such as enlarged tonsils and adenoids have an increased risk of developing nervous system tumors. The risk is highest for schwannomas (RR ...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • Members of a cohort of 4,296 patients who received conventional (200 kV) radiation treatment to the head and neck for benign conditions before their 16th birthday.
  • All of the patients were treated at Michael Reese Hospital, Chicago, between 1939 and 1962.

Exclusion

    Key Trial Info

    Start Date :

    August 1 1996

    Trial Type :

    OBSERVATIONAL

    End Date :

    July 1 2006

    Estimated Enrollment :

    112 Patients enrolled

    Trial Details

    Trial ID

    NCT00340496

    Start Date

    August 1 1996

    End Date

    July 1 2006

    Last Update

    March 4 2008

    Active Locations (1)

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    1

    National Cancer Institute (NCI)

    Bethesda, Maryland, United States, 20892