Status:
COMPLETED
Diet and Genetic Damage
Lead Sponsor:
National Institute of Environmental Health Sciences (NIEHS)
Conditions:
Diet
Eligibility:
All Genders
18-45 years
Brief Summary
This study will examine the risks and protective effects of dietary factors on temporary genetic damage to cells lining the gastrointestinal tract and to blood cells. Some foods, including very well d...
Detailed Description
Colorectal cancer is one of the most common forms of cancer worldwide and is the second leading cause of cancer death in the United States. Given the frequency of occurrence and the poor prognosis for...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Nonsmoking, English speaking, healthy adults, ages 18-45 will be enrolled.
- EXCLUSION CRITERIA:
- Pregnant women will be excluded, as the dietary regimen in this study is not optimal for pregnant women.
- Individuals will also be excluded if they consume more than two alcoholic drinks per day, have a history of illicit drug use, have a history of goiter, diabetes, colitis, or a diagnosed current thyroid condition, are excessively obese (BMI greater than 30), are vegetarians, or are currently taking anti-coagulant medication.
- Individuals on prescription medications or antibiotics will be excluded.
- Consumption of tea, or use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), or vitamin or herbal supplements by participants will also be prohibited during the study.
- Alcohol consumption will be prohibited during the study.
- Children will not be enrolled in the study.
Exclusion
Key Trial Info
Start Date :
April 21 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 16 2019
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00340743
Start Date
April 21 2004
End Date
July 16 2019
Last Update
July 18 2019
Active Locations (1)
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1
University of North Carolina
Chapel Hill, North Carolina, United States, 27599-7030