Status:
COMPLETED
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s)
Lead Sponsor:
National Cancer Institute (NCI)
Conditions:
Nasopharyngeal Carcinoma
Eligibility:
All Genders
7-90 years
Brief Summary
The objective of this study is to characterize genes associated either with susceptibility or resistance to the development nasopharyngeal carcinoma (NPC) in a Chinese population where the incidence o...
Detailed Description
The objective of this study is to characterize genes associated either with susceptibility or resistance to the development nasopharyngeal carcinoma (NPC) in a Chinese population where the incidence o...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Individuals must meet the following eligibility criteria to be entered into the NPC study.
- Cohort A: Proband: NPC positive (stage III or IV), age less than 50 at time of NPC diagnosis, and EBV/IgA/VCA positive. Spouse of Proband. Child of proband and of spouse (or a parent of the proband)
- Cohort B: EBV/IgA/VCA positive 12 years ago and NPC negative. Spouse of proband. Child of proband and of spouse (or a parent of the proband).
- EXCLUSION CRITERIA:
- Persons with any of the following will be excluded from the study.
- Persons who are unwilling or unable to given informed consent, or whose spouse and child(ren) (or parent) are willing to participate and give informed consent/assent.
- Persons with no living spouse of child(ren)/parent.
Exclusion
Key Trial Info
Start Date :
April 1 2001
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 20 2006
Estimated Enrollment :
6490 Patients enrolled
Trial Details
Trial ID
NCT00341146
Start Date
April 1 2001
End Date
September 20 2006
Last Update
June 16 2020
Active Locations (1)
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1
Institute for Viral Disease Control & Prevention
Beijing, China