Status:
COMPLETED
Studies of Thyroid Abnormalities in Northeastern Kazakhstan Associated With Nuclear Weapons Testing
Lead Sponsor:
National Cancer Institute (NCI)
Conditions:
Thyroid Cancer
Eligibility:
All Genders
63-71 years
Brief Summary
We propose to study the prevalence of thyroid nodules and cancer in relation to radiation dose, in a defined cohort of Kazakhstan residents exposed as children to radioactive fallout from atomic bomb ...
Detailed Description
We propose to study the prevalence of thyroid nodules and cancer in relation to radiation dose, in a defined cohort of Kazakhstan residents exposed as children to radioactive fallout from atomic bomb ...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Subjects will be selected in accordance with the research aims of the project.
- The majority should have whole-body or bone marrow radiation dose estimates as high as available among subjects who were children at the time of the major fallout events.
- Few presumably low-exposure subjects are needed as null controls.
- All subjects should have been born between 1940 and 1948.
- EXCLUSION CRITERIA:
- Subjects must not have a medical history including radiation therapy or high-dose diagnostic radiography or been treated for cancer.
Exclusion
Key Trial Info
Start Date :
March 5 1998
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 18 2016
Estimated Enrollment :
2997 Patients enrolled
Trial Details
Trial ID
NCT00341185
Start Date
March 5 1998
End Date
November 18 2016
Last Update
December 16 2019
Active Locations (1)
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1
Semipalatinsk State Medical Academy
Semipalatinsk, Kazakhstan