Status:

COMPLETED

A Pilot Study to Evaluate the Efficacy of Refined Methods to Mitigate Indoor Allergens in North Carolina and Boston, Massachusetts Homes

Lead Sponsor:

National Institute of Environmental Health Sciences (NIEHS)

Conditions:

Hypersensitivity

Eligibility:

All Genders

21+ years

Brief Summary

A Pilot Study to Evaluate the Efficacy of Refined Methods to Mitigate Indoor Allergens in North Carolina and Boston, Massachusetts Homes

Detailed Description

We propose to conduct a study to evaluate the efficacy of an intensive cockroach and cockroach allergen removal program to mitigate cockroach allergen levels in house dust to less than 8 Units Bla g1 ...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • To be eligible for the study, each home must:
  • have a home occupant who intends to live at the same address for at least 6 months;
  • have a home occupant live at the house full time;
  • have a home occupant that is at least 21 years of age;
  • have at least one bedroom with wall to wall carpeting.
  • Yield dust collected during the screening visit that contains combined Der f I plus Der p I allergen levels of greater than or equal to 10 ug/gram dust.
  • For the intervention arm only:
  • home occupant must have an adult at home during the study visits on weekdays over the six month period that the study is ongoing.
  • EXCLUSION CRITERIA:
  • Homes will be excluded from this study if any of the inclusion criteria are not met.
  • Indoor Dust Mite Allergen:
  • Must have a home occupant who intends to live at the same address for at least 6 months; live at the house full time; be at least 21 years of age; have at least one bedroom with wall to wall carpeting; yield dust collected during the screening visit that contains combined Def fl plus Der pl allergen levels of greater than or equal to 10 ug/gram dust.
  • For Intervention arm only - home occupant must have an adult at home during the study visits on weekdays over the six month period that the study is ongoing.
  • Indoor Cockroach Allergen:
  • Must have a home occupant that intends to live at the same address for at least 6 months; live in the house full time; be at least 21 years of age; have moderate to severe cockroach infestation as evidenced by occupant self-reports of cockroach sightings and by sticky trap assessment that yield a combined total sticky trap count of 50-250 cockroaches.
  • For intervention arm only - home occupant must have an adult at home during most of the weekdays over the six month period that the study is ongoing.

Exclusion

    Key Trial Info

    Start Date :

    October 19 2000

    Trial Type :

    OBSERVATIONAL

    End Date :

    September 11 2006

    Estimated Enrollment :

    88 Patients enrolled

    Trial Details

    Trial ID

    NCT00344344

    Start Date

    October 19 2000

    End Date

    September 11 2006

    Last Update

    July 2 2017

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    National Institute of Environmental Health Sciences (NIEHS)

    Bethesda, Maryland, United States, 20892