Status:

COMPLETED

Appetite-Related Brain Activity in Women With Anorexia Nervosa

Lead Sponsor:

New York State Psychiatric Institute

Conditions:

Eating Disorders

Anorexia Nervosa

Eligibility:

FEMALE

18-45 years

Brief Summary

This study will use functional magnetic resonance imaging to compare appetite-related brain activity in women with anorexia nervosa before and after receiving treatment for the disorder.

Detailed Description

Anorexia nervosa (AN) is a serious eating disorder that is characterized by an extreme loss of appetite. People with AN view themselves as overweight and cannot bring themselves to eat, even though mo...

Eligibility Criteria

Inclusion

  • For Participants with AN:
  • DSM-IV diagnosis of AN (restricting or binge eating/purging subtype)
  • Medically stable (not continuing to lose weight and vital signs stable)
  • For Healthy Participants:
  • Currently weighs 80-120% of ideal weight
  • no history of binge eating disorder or vomiting
  • no current or past psychiatric illness

Exclusion

  • For Participants with AN:
  • Currently taking medication
  • Current substance abuse or dependence disorder
  • History of suicide attempt or other self-injurious behavior within 6 months prior to study entry
  • Non-removable metal on or inside the body (e.g., metal pacemaker, surgical clips, metallic-ink tattoos)
  • For Healthy Participants:
  • Current or past psychiatric illness
  • History of binge eating or vomiting
  • Any significant medical or neurologic illness
  • Currently taking medication
  • History of drug or alcohol abuse within 3 months prior to study entry
  • Non-removable metal on or inside the body (e.g., metal pacemaker, surgical clips, metallic-ink tattoos)

Key Trial Info

Start Date :

October 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2010

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT00344656

Start Date

October 1 2004

End Date

October 1 2010

Last Update

April 19 2012

Active Locations (1)

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New York State Psychiatric Institute

New York, New York, United States, 10032