Status:
COMPLETED
Short Term Effects of HMG-CoA Reductase Inhibition (Atorvastatin)on Renal Hemodynamics, Tubular Function and Vasoactive Hormones on Healthy Subjects
Lead Sponsor:
Regional Hospital Holstebro
Conditions:
Healthy
Eligibility:
All Genders
20-50 years
Phase:
PHASE4
Brief Summary
We wanted to test the shortterm effects of HMG-CoA reductase inhibition (atorvastatin) on renal hemodynamics, renal tubular function and vasoactive hormones on healthy subjects.
Eligibility Criteria
Inclusion
- Both men and women
- Age: Between 20-50
- BMI\<30
Exclusion
- Cl. signs or history of disease of heart, lungs, kidneys or endocrine organs.
- Abnormal lab. tests( haemoglobin, pl. sodium, pl. potassium, pl.creatinine, pl.bilirubin, pl.ALAT, pl. cholesterol, blood glucose)
- Albuminuria or glucosuria
- Cancer
- Art. hypertension
- Alcohol abuse
- Med. treatment, except oral contraceptives
- Pregnancy or breast feeding
- Blood donation less than 1 month before study
Key Trial Info
Start Date :
September 1 2004
Trial Type :
INTERVENTIONAL
End Date :
February 1 2005
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00345202
Start Date
September 1 2004
End Date
February 1 2005
Last Update
May 15 2008
Active Locations (1)
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1
Medical research unit, Department of medicin, Holstebro Sygehus
Holstebro, Ringkøbing Countie, Denmark, 7500