Status:
UNKNOWN
Asymptomatic Narrow Angles - Laser Iridotomy Study; Multicentric RCT
Lead Sponsor:
Singapore National Eye Centre
Collaborating Sponsors:
National Medical Research Council (NMRC), Singapore
Conditions:
Asymptomatic Narrow Angles
Primary Angle Closure Suspects
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
This is a multicentric, randomised, controlled study comparing Laser Iridotomy (LI) to no treatment in subjects with asymptomatic narrow angles (ANA).One eye of each subject with ANA will be randomise...
Detailed Description
Objective: This study will compare LI versus no treatment in subjects with asymptomatic narrow angles, the anatomical trait that predisposes to primary angle closure glaucoma (PACG), in order to asses...
Eligibility Criteria
Inclusion
- Bilateral Narrow angles
- Age 50 years and above
- Informed consent obtained prior to or at baseline visit
Exclusion
- Presence of PAS
- IOP \> 21 mm Hg
- Glaucomatous optic neuropathy and/or CDR \> 0.7
- Secondary angle closure such as uveitis, neovascularisation etc.
- Prior intraocular surgery or penetrating eye injury
- Corneal disorders such as corneal endothelial dystrophy except mild corneal guttae
- Evidence of prior acute angle closure event
- High risk of acute angle closure.
- Significant cataract and visual acuity less than 20/40
- Constant use of contact lens for refractive correction
- Chronic use of topical or systemic steroids
- Established retinopathies on ocular treatments (e.g. Diabetic)
- Any other disease which is likely to cause field loss in next 3 years
- Severe health problems decreasing life expectancy to less than one year.
Key Trial Info
Start Date :
January 1 2005
Trial Type :
INTERVENTIONAL
End Date :
January 1 2013
Estimated Enrollment :
544 Patients enrolled
Trial Details
Trial ID
NCT00347178
Start Date
January 1 2005
End Date
January 1 2013
Last Update
July 4 2006
Active Locations (1)
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1
Singapore Eye Research Institute
Singapore, Singapore, 168751