Status:
WITHDRAWN
Newcastle Disease Virus (NDV) for Cancer Patients Resistant to Conventional Anti-cancer Modalities
Lead Sponsor:
Hadassah Medical Organization
Conditions:
Metastatic Cancer
Newcastle Disease Virus (NDV)
Eligibility:
All Genders
Phase:
PHASE2
Brief Summary
NDV is a virus tht is harmful in chicken, but harmless in man. There are 2 major sub-strains of NDV, one oncolytic and one non-oncolytic. Oncolytic NDV (MTH-68H) preferentially homes and replicates in...
Eligibility Criteria
Inclusion
- Patients with the following disease category will be eligible:
- Patients with metastatic lung cancer, metastatic GI cancer, metastatic urogenital cancer, skin and soft tissue cancer.
- Failure to anti-cancer modalties and evidence of progressive disease despite optimal application of all relevant available anti-cancer modalities.
- Consenting patients.
- The patient should sign a consent form stating that he/she will make sure to avoid any contact with chicken or any other species of birds.
Exclusion
- Not fulfilling any of the above criteria.
- Moribund patients or patients with life-expectancy \<3 months.
- Karnofsky performance status \<60%.
- Pregnant or lactating women.
- Active local or systemic infections requiring treatment.
- Co-morbidity or life-threatening clinical condtion other than the basic cancer.
Key Trial Info
Start Date :
March 1 2006
Trial Type :
INTERVENTIONAL
End Date :
June 1 2006
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00348842
Start Date
March 1 2006
End Date
June 1 2006
Last Update
April 8 2011
Active Locations (1)
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1
Hadassah Medical Organization
Jerusalem, Israel, 91120