Status:
UNKNOWN
Does Sildenafil Protect Against Pulmonary Related Complications Following Cardiopulmonary Bypass?
Lead Sponsor:
NHS Greater Glasgow Yorkhill Division
Conditions:
Cardiopulmonary Bypass
Eligibility:
All Genders
3-5 years
Phase:
PHASE4
Brief Summary
Does pre-operative administration of Sildenafil (Viagra, Pfizer) reduce the lung injury associated with cardiopulmonary bypass in children undergoing corrective surgical repair of congenital heart dis...
Eligibility Criteria
Inclusion
- Paediatric patients undergoing open heart surgery utilising cardiopulmonary bypass to correct acyanotic congenital heart disease.
- Age \> 3 months Parents that show a good understanding of their child's condition and are happy for their child to participate in the study.
Exclusion
- Patients with known organ dysfunction prior to surgery (pulmonary, renal or hepatic) Communication barrier resulting in poor basic comprehension of the proposed study (e.g. language barrier) Patients with cyanotic heart disease Patients undergoing heart surgery without the use of cardiopulmonary bypass Patients who do not tolerate oral Sildenafil (e.g. Vomiting) or whose surgery is subsequently cancelled.
Key Trial Info
Start Date :
June 1 2006
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00350441
Start Date
June 1 2006
Last Update
October 11 2006
Active Locations (1)
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1
Royal Hospital for Sick Children
Glasgow, Strathclyde, United Kingdom, G3 8SJ