Status:
TERMINATED
Does Montelukast Have an Affect on the Function of the Artery in Patients With Heart Disease
Lead Sponsor:
University of Calgary
Collaborating Sponsors:
Foothills Interventional Cardiology Group
Conditions:
Coronary Artery Disease
Acute Coronary Syndrome
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
To evaluate the effect of the drug Montelukast on the brachial artery's function. By giving a drug like Montelukast, which blocks the effects of inflammation in the lungs arteries and controls asthma,...
Detailed Description
To measure the benefit of cysteinyl leukotriene blockade in favourably altering the pathophysiology of coronary artery disease. We hypothesize that patients admitted to hospital with acute coronary sy...
Eligibility Criteria
Inclusion
- male or female age 18-80 years, diagnosis of acute coronary syndrome with one increased Troponin assay,chest pain or chest pain syndrome, stable on initial medical therapy, painfree x 6 hours prior to enrollment
Exclusion
- STEMI, Q-wave MI, \< 18years, women of childbearing potential, new LBBB, recurrent chest pain since hospitalization, IV nitroglycerine drip, hemodynamically unstable, history of asthma, history of liver disease or abnormal liver enzymes
Key Trial Info
Start Date :
July 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2010
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00351364
Start Date
July 1 2006
End Date
July 1 2010
Last Update
December 3 2014
Active Locations (1)
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1
Foothills Medical Center
Calgary, Alberta, Canada, T2N 2T9