Status:
COMPLETED
Lung Tumour Volume Database
Lead Sponsor:
Trans Tasman Radiation Oncology Group
Collaborating Sponsors:
Peter MacCallum Cancer Centre, Australia
Conditions:
Non-Small Cell Lung Cancer
Eligibility:
All Genders
18+ years
Brief Summary
The main aim is to determine, in patients with locoregional, non-small cell lung cancer (NSCLC) treated by definitive radiotherapy, the influence on survival of the volume of primary tumour, as measur...
Detailed Description
Patients with locoregional non small cell lung cancer are registered on study after tumour volumes are outlined by a radiologist and prior to the commencement of any treatment. All patients must have...
Eligibility Criteria
Inclusion
- Must satisfy ALL of the following
- NSCLC - histological or cytological diagnosis of non-small cell lung cancer
- Intra-thoracic disease - disease is confined to the primary site, with or without intrathoracic lymph nodes
- CT planning - CT imaging of the thorax has been performed as part of the planning procedure
- Definitive radiotherapy - it is planned to give definitive radiotherapy with or without chemotherapy (prior to, during or after radiotherapy). Definitive radiotherapy is defined as 60 Gy in 6 weeks, 50 Gy in 4 weeks or at least the equivalent of either of these. The size of each individual; fraction should not exceed 2.5 Gy.
- Measurable disease - the primary tumour and nodes with maximum diameter greater than 1cm represent measurable disease
Exclusion
- A patient satisfying ANY of the following is ineligible
- Symptomatic or radiological evidence of metastatic disease
- Prior treatment for non-small cell lung cancer
- Surgical resection is part of initial treatment
- Palliative radiotherapy planned
Key Trial Info
Start Date :
September 1 1999
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2012
Estimated Enrollment :
531 Patients enrolled
Trial Details
Trial ID
NCT00351598
Start Date
September 1 1999
End Date
November 1 2012
Last Update
August 4 2014
Active Locations (15)
Enter a location and click search to find clinical trials sorted by distance.
1
St George Hospital
Kogarah, New South Wales, Australia, 2217
2
Liverpool Hospital
Liverpool, New South Wales, Australia, 1871
3
Newcastle Mater Misericordiae Hospital
Newcastle, New South Wales, Australia, 2298
4
Royal Prince Alfred Hospital
Sydney, New South Wales, Australia, 2050