Status:

COMPLETED

Immunogenicity & Safety Study of Combined/Separate Vaccine(s) Against Common Diseases in Infants (2,4,6 Months of Age).

Lead Sponsor:

GlaxoSmithKline

Conditions:

Poliomyelitis

Tetanus

Eligibility:

All Genders

Up to 7 years

Phase:

PHASE3

Brief Summary

This study will evaluate the immunogenicity of the co-administration of different combinations of DTPa, IPV, hepatitis B, Hib and Men C vaccines during the first year of life.

Eligibility Criteria

Inclusion

  • Healthy male or female infant between, \& including, 0 \& 7 days of age at the time of the inclusion. Born after a normal gestation period (between 36 \& 42 weeks).
  • Written informed consent obtained from the parent/guardian of the subject.

Exclusion

  • Use of any investigational or non-registered product (drug or vaccine) other than the study vaccine(s) or planned use during the study period.
  • Administration of immunosuppressants or other immune-modifying drugs from birth.
  • Administration of immunoglobulins and/or any blood products since birth or planned administration during the study period.
  • Administration / planned administration of a vaccine not foreseen by the study protocol during the period starting from birth and ending 30 days after the last dose except BCG vaccination if given before the 30-day period preceding the administration of the 1st dose of Infanrix penta™ or Infanrix hexa™ in combination with a meningococcal C vaccine.
  • Evidence of previous or intercurrent diphtheria, tetanus, pertussis, polio, hepatitis B, meningococcal C and Hib disease.
  • Evidence of previous diphtheria, tetanus, pertussis, polio, hepatitis B, meningococcal C and Hib vaccination.

Key Trial Info

Start Date :

September 30 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 16 2004

Estimated Enrollment :

480 Patients enrolled

Trial Details

Trial ID

NCT00352963

Start Date

September 30 2003

End Date

July 16 2004

Last Update

January 6 2020

Active Locations (22)

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Page 1 of 6 (22 locations)

1

GSK Investigational Site

Alcorcón, Spain, 28922

2

GSK Investigational Site

Almeira, Spain, 4009

3

GSK Investigational Site

Badalona, Spain, 08916

4

GSK Investigational Site

Barcelona, Spain, 08025