Status:
UNKNOWN
A Study of the Effect of Time on Topical Anesthetic Efficacy.
Lead Sponsor:
University of Toronto
Conditions:
Pain
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
This is a study of the effect of time on the effectiveness of topical anesthetics in the mouth. The Null Hypothesis is: Regardless of the time of application over a 10-minute period, there is no diffe...
Detailed Description
The study design will be a double blind randomized controlled split-mouth clinical trial. It is proposed to compare the effectiveness of the standard topical anesthetic 5% lidocaine with a placebo ove...
Eligibility Criteria
Inclusion
- In good health (ASA 1 or ASA 2)
- Weight between 40-100kg, inclusive.
- Between ages 18-70, inclusive.
- Informed consent
Exclusion
- ASA 3 or higher.
- History of allergy to sulfites, lidocaine or mepivacaine.
- Taking any analgesic 48hrs before testing, such as an NSAID, opioid, or acetaminophen.
- Pregnancy.
- Recent oral trauma.
- Lack of informed consent.
Key Trial Info
Start Date :
July 1 2006
Trial Type :
INTERVENTIONAL
End Date :
December 1 2006
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00353041
Start Date
July 1 2006
End Date
December 1 2006
Last Update
July 17 2006
Active Locations (1)
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1
Faculty of Dentistry
Toronto, Ontario, Canada, M5G 1G6