Status:
COMPLETED
The Effect of Oxygen Exposure During Newborn Resuscitation on Lung Injury
Lead Sponsor:
University of Calgary
Collaborating Sponsors:
Equipment loan from Masimo Corp.
Conditions:
Prematurity
Oxidative Pulmonary Injury
Eligibility:
All Genders
23-32 years
Phase:
NA
Brief Summary
Hypothesis: In this feasibility study, hyperoxemia, as approximated by transcutaneous hemoglobin saturation with oxygen (Sp02), at the time of birth will cause sustained pulmonary oxidative stress as ...
Detailed Description
Immediately prior to birth, preterm infants (\<= 32 weeks gestation) will be randomized to one of three groups: 1. Low Oxygen Burden (LOB) - initiation of resuscitation with 21% 02, II. Moderate Oxyge...
Eligibility Criteria
Inclusion
- \<=32 weeks gestation
- inborn
- require intubation
Exclusion
- lethal anomalies
- cyanotic congenital heart disease
- known hemoglobinopathy
- risk factors for persistent pulmonary hypertension
Key Trial Info
Start Date :
July 1 2005
Trial Type :
INTERVENTIONAL
End Date :
October 1 2006
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00355875
Start Date
July 1 2005
End Date
October 1 2006
Last Update
November 7 2006
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Canada
Calgary, Alberta, Canada, T2N 2T9