Status:
COMPLETED
Genetic Studies to Identify Stroke Subtypes and Outcome
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Cerebrovascular Disease
Stroke
Eligibility:
All Genders
21+ years
Brief Summary
This study will characterize the gene response of the body's immune and inflammatory cells to stroke. There is a wide variation in stroke risk, stroke outcome, and response to clot-busting therapy for...
Detailed Description
Background: In the United States, stroke is the third most common cause of death and the leading cause of adult disability. Despite the many efforts to find effective treatment for stroke there is at ...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- HEALTHY VOLUNTEERS:
- Over age 21
- Healthy
- Willing to participate in the study
- Informed consent obtained
- ACUTE STROKE PATIENTS:
- Stroke patients admitted to Suburban or Holy Cross Hospitals
- Over age 21
- Willing to participate in the study
- Informed Consent obtained
- EXCLUSION CRITERIA:
- HEALTHY VOLUNTEERS:
- Active medical problems
- Current symptomatic infection
- Current severe allergic disorders
- STROKE PATIENTS:
- Cardiovascular instability
- Severe anemia (hemoglobin less than 8.0 gm/dl)
- Hemorrhagic diathesis
- Current infection
- Current severe allergic disorders
Exclusion
Key Trial Info
Start Date :
June 3 2002
Trial Type :
OBSERVATIONAL
End Date :
December 15 2008
Estimated Enrollment :
840 Patients enrolled
Trial Details
Trial ID
NCT00357513
Start Date
June 3 2002
End Date
December 15 2008
Last Update
July 2 2017
Active Locations (3)
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1
Suburban Hospital
Bethesda, Maryland, United States, 20814
2
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
3
Holy Cross Hospital, Silver Spring
Silver Spring, Maryland, United States, 20902