Status:
COMPLETED
Role of the Brain in Processing Visually Presented Objects
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Healthy
Motor Skills
Eligibility:
All Genders
20-60 years
Brief Summary
This study will examine the parts of the brain that use visual information to perform movements. Patients with certain brain lesions tend to have difficulty in processing visually presented objects. T...
Detailed Description
Objectives: Patients with frontal lobe lesions tend to grasp visually presented objects automatically and forcefully (forced grasping). Grasping of a milder form is seen in infants and the aged popula...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Healthy male or female subjects between the ages of 20 and 60 years old will be eligible within the limits of the exclusion criteria below.
- EXCLUSION CRITERIA:
- A previous history of neurological diseases will be carefully taken by direct interview by the Principal or Associate Investigators. Subjects who had a head injury (severe enough to cause loss of consciousness) or other brain diseases causing mental disturbance, sensory impairment, or motor dysfunction in the past will be excluded. Subjects who have metals either in the mouth, such as dental prostheses, or in the head, such as surgical clips from any previous surgical procedures, are also excluded due to technical limitations in terms of MEG. Furthermore, subjects wearing glasses for visual correction and those with poor vision, even with contact lenses, are excluded also due to technical limitations for MEG. Subjects who have pacemakers or other implanted electrical devices, brain stimulators, dental implants, aneurysm clips (metal clips on the wall of a large artery), metallic prostheses (including metal pins and rods, heart valves, and cochlear implants), permanent eyeliner, implanted delivery pump, or shrapnel fragments, and welders and metal workers are excluded for MRI for the sake of safety of subjects. Finally, by doing a brief neurological examination of finger movements, the subjects with poor performance of fine finger movements or those who are judged to have mirror movements will be excluded.
Exclusion
Key Trial Info
Start Date :
November 18 2003
Trial Type :
OBSERVATIONAL
End Date :
October 28 2008
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT00357695
Start Date
November 18 2003
End Date
October 28 2008
Last Update
July 2 2017
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892