Status:
WITHDRAWN
RU-486 in the Treatment of Bipolar Depression
Lead Sponsor:
University of British Columbia
Collaborating Sponsors:
Western Economic Diversification Canada
Stanley Medical Research Institute
Conditions:
Bipolar Depression
Eligibility:
All Genders
19-65 years
Phase:
PHASE2
Brief Summary
Bipolar disorder is a chronic and recurrent illness which involves episodes of mania and depression. It is believed that disturbance of the stress hormone system (the hypothalamic-pituitary-adrenal or...
Detailed Description
Detailed Description: This study will be a parallel design randomized control trial. Duration of study is 10 weeks per subject. Following a baseline assessment of neurocognitive performance, mood sym...
Eligibility Criteria
Inclusion
- Male \& female outpatients between 19-65 years of age with a diagnosis of bipolar depression. Women must not be currently pregnant and must use a reliable method of contraception for the duration of the study. Subjects must be on stable medication (4 weeks minimum) for their bipolar illness. Subjects must be able to provide written informed consent. Subjects must adequately understand written \& verbal English as rating scales as neurocognitive tests are only in English.
Exclusion
- Those not meeting the above criteria and those not competent to give informed consent. Women who are currently pregnant. Also excluded: those who have a clinically significant medical illness (including significant head injury with loss of consciousness), those at immediate risk of harming self or others, are currently abusing alcohol or drugs, those with a neurological disorder or uncompensated endocrine disorder, those with a known allergy to mifepristone, those currently being treated with an investigational medication or medication that is contraindicated with mifepristone.
Key Trial Info
Start Date :
July 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00359125
Start Date
July 1 2006
End Date
December 1 2010
Last Update
January 22 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of British Columbia, Dept. of Psychiatry
Vancouver, British Columbia, Canada, V6T 1Z3