Status:
UNKNOWN
The Effect of Glyceryl Trinitate and Diamox on Cerebral Haemodynamics.
Lead Sponsor:
Danish Headache Center
Conditions:
Migraine
Eligibility:
All Genders
18-55 years
Phase:
NA
Brief Summary
After infusion / injection of Glyceryl trinitrate and Diamox it is wished to study the effect of drugs on the cerebral haemodynamics such as Cerebral blod flow and cerebral blod volume.
Detailed Description
Experimental headache model open a unike opportunity to study the pathophysiological mechanisms behind headache in general and migrane in particular. Previous studies have used various techniques to s...
Eligibility Criteria
Inclusion
- healthy volunteers; men and women age 18-50 years.
- weight 50-100 kg
Exclusion
- Tension type headache more then once per month during the last year.
- Other primary headache types.
- Daily use of medication.
- Pregnant or lactating women.
- Headache on the trail day or 24 hours prior to the trial.
- Contraindications to MRI.
- Hypotension og hypertension.
- Other significant medical conditions judged by the doctor in charge.
Key Trial Info
Start Date :
August 1 2006
Trial Type :
INTERVENTIONAL
End Date :
May 1 2007
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00363571
Start Date
August 1 2006
End Date
May 1 2007
Last Update
August 15 2006
Active Locations (1)
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1
Danish Headache Center, Neurological Dep. Glostrup hospital
Glostrup Municipality, Denmark, 2770