Status:
COMPLETED
Understanding the Genetic Basis of Familial Combined Hyperlipidemia in Mexican Individuals
Lead Sponsor:
University of California, Los Angeles
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Hyperlipidemia, Familial Combined
Coronary Disease
Eligibility:
All Genders
10-80 years
Brief Summary
Familial combined hyperlipidemia (FCHL) is an inherited disorder characterized by elevated levels of cholesterol and triglycerides; it often occurs in Mexican individuals with coronary heart disease (...
Detailed Description
CHD is the leading cause of death in Mexico. Dyslipidemia that is characterized by high total cholesterol, high triglycerides, and low "good" high-density lipoprotein (HDL) cholesterol is a risk facto...
Eligibility Criteria
Inclusion
- Elevated levels of serum total cholesterol, triglycerides, or both
- Elevated levels of serum apolipoprotein B (using the Mexican population percentiles)
Exclusion
- Tendon xanthomas
- Kidney disease
- Thyroid disorder
Key Trial Info
Start Date :
July 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2011
Estimated Enrollment :
998 Patients enrolled
Trial Details
Trial ID
NCT00365235
Start Date
July 1 2006
End Date
June 1 2011
Last Update
January 12 2012
Active Locations (1)
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1
Instituto Nacional De Ciencias Medicas y Nutricion
Mexico City, Mexico, 14000