Status:
COMPLETED
3 Months' Versus 6 Months' Anticoagulation in Patients With DVT and/or PE
Lead Sponsor:
British Thoracic Society
Conditions:
Deep Vein Thrombosis
Pulmonary Embolism
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
To determine whether 3 months' anticoagulation is as good as or better than 6 months' for the treatment of DVT/PE
Detailed Description
Multi-centre trial involving 46 hospitals in the United Kingdom, with patients entered by 137 Consultant Physicians. Consenting patients were randomised in a central office to either 3 months' or 6 mo...
Eligibility Criteria
Inclusion
- Patients aged 18 years or more with suspected or proven DVT/PE whom the clinician intended to anticoagulate.
Exclusion
- DVT/PE severe enough to require thrombolysis or pulmonary embolectomy.
- DVT/PE in the preceding 3 years.
- Neoplasia diagnosed/treated within previous 3 years.
- Pregnancy.
- Known major thrombophilias.
- Prolonged or continuous immobility or confinement to bed.
- Previous allergy to heparin or warfarin.
- Requirement for long-term anticoagulation.
- Inability to give informed consent.
Key Trial Info
Start Date :
September 1 1999
Trial Type :
INTERVENTIONAL
End Date :
December 1 2003
Estimated Enrollment :
2400 Patients enrolled
Trial Details
Trial ID
NCT00365950
Start Date
September 1 1999
End Date
December 1 2003
Last Update
August 18 2006
Active Locations (2)
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1
Department of Chest Medicine, Llandough Hospital
Cardiff, Wales, United Kingdom, CF62 2XX
2
Department of Chest Medicine, Llandough Hospital,
Cardiff, Wales, United Kingdom, CF64 2XX