Status:

TERMINATED

Study Comparing Bifeprunox to Risperidone in Treatment of Outpatients With Schizophrenia With Weight as Primary Endpoint

Lead Sponsor:

Wyeth is now a wholly owned subsidiary of Pfizer

Collaborating Sponsors:

Solvay Pharmaceuticals

Conditions:

Schizophrenia

Eligibility:

All Genders

18-65 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to determine the effect of bifeprunox or risperidone on the body weight of patients with schizophrenia.

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Current treatment of at least 3 months with risperidone.
  • Primary diagnosis of schizophrenia.
  • Total Positive and Negative Symptoms Scale (PANSS) score \< or = 70 at screening and baseline.
  • Exclusion criteria:
  • Psychiatric diagnosis other than schizophrenia as assessed by the modified Mini International Neuropsychiatric Interview (MINI) and considered by the investigator to be the primary psychiatric diagnosis.
  • History or presence of clinically significant cardiovascular, endocrine, hepatic, renal or other medical disease that might be detrimental to the subject or confound the study.
  • History of any suicide attempt within 3 years of day 1 or significant immediate risk of violence or suicidality.

Exclusion

    Key Trial Info

    Start Date :

    November 1 2006

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    March 1 2008

    Estimated Enrollment :

    400 Patients enrolled

    Trial Details

    Trial ID

    NCT00366704

    Start Date

    November 1 2006

    End Date

    March 1 2008

    Last Update

    February 11 2013

    Active Locations (66)

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    Page 1 of 17 (66 locations)

    1

    Little Rock, Arkansas, United States, 72201

    2

    Little Rock, Arkansas, United States, 72211

    3

    Anaheim, California, United States, 92802

    4

    Anaheim, California, United States, 92804

    Study Comparing Bifeprunox to Risperidone in Treatment of Outpatients With Schizophrenia With Weight as Primary Endpoint | DecenTrialz