Status:
TERMINATED
Endocrine and Psychological Evaluation of Adopted Children
Lead Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions:
Psychosocial Adjustment
Eligibility:
All Genders
10-4 years
Brief Summary
The deleterious effects of institutionalized care on the health and growth and development of children have been described. Early studies have shown that the effects of institutionalized care on a chi...
Detailed Description
The deleterious effects of institutionalized care on the health and growth and development of children have been described. Early studies have shown that the effects of institutionalized care on a chi...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- A. The patient sample will be children ages 10 months to 4 years old (pre-pubertal, Tanner I) referred to the International Adoption Center or Johns Hopkins University Medical Center for an initial evaluation within two to four weeks after they arrive from their country of origin (Eastern Europe/Russia).
- A total of 60 children, ages 10 months to 6 years, will be recruited for a control group and will be frequency matched with the adopted subjects into four strata: 10 to 42 month old boys, 10 to 42 month old girls, 43 to 72 month old boys, and 43 to 72 month old girls.
- The controls will be healthy children with no history of medical or psychological disorders
- The controls will be healthy children with no history of medical or psychological disorders.
- EXCLUSION CRITERIA:
- Children with known documented growth hormone deficiency, and/or history of chronic illness such as renal failure, severe chronic lung disease (restrictive, obstructive) diabetes, hypothyroidism.
- Children with known genetic or chromosomal abnormalities.
- Children with medical conditions known to be associated with permanent developmental delay (i.e. fetal alcohol syndrome).
- Children with chronic medication use.
- Children with behavior problems receiving psychiatric treatment
- Children with documented infectious diseases (AIDS, Hepatitis, etc).
- Children with clinical signs of puberty; only children in Tanner-I pubertal stage will be allowed in the study.
Exclusion
Key Trial Info
Start Date :
August 18 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 30 2015
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT00368043
Start Date
August 18 2006
End Date
March 30 2015
Last Update
December 17 2019
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892