Status:
WITHDRAWN
KONVERT-AF - Relevance of Point in Time for Conversion of Acute Atrial Fibrillation
Lead Sponsor:
Atrial Fibrillation Network
Collaborating Sponsors:
German Federal Ministry of Education and Research
Conditions:
Atrial Fibrillation
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
To investigate if in acute symptomatic atrial fibrillation (AF) the early (\>2 hrs but within 12 hrs of the beginning of the arrhythmia) electrical cardioversion leads to a longer recurrence-free inte...
Detailed Description
So far it is unknown if early or delayed cardioversion is most beneficial for patient outcome and which strategy is best to prevent recurrence of AF. The KONVERT-AF trial investigates if in acute symp...
Eligibility Criteria
Inclusion
- documented AF that began between 2 and 8 hrs before randomization
- indication for electrical cardioversion.
- age above 18 yrs
- written informed consent
Exclusion
- AF caused by not adequately treated reversible conditions(e.g. myocardial infarction, thyrotoxicosis, ethanol intoxication, infection, pericarditis, surgery)
- newly initiated (i.e. within 7 days before randomization) antiarrhythmic agents of class I, II and/or III
- catheter ablation of AF within 3 months before randomization
- pacemaker or icd
- myocardial infarction within 3 months before randomization
- urgent need to cardioversion of AF because of associated potentially dangerous symptoms such as chest pain, syncope, dyspnea
- contraindications for therapy with vitamin k-antagonists
- intracardial thrombus
- primary indication for pharmacological cardioversion
- in females: pregnancy, lactation period or no sufficient contraception within last 3 months
Key Trial Info
Start Date :
September 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00369330
Start Date
September 1 2006
Last Update
September 3 2012
Active Locations (1)
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1
Medizinische Klinik und Poliklinik II, University Hospital of Bonn
Bonn, Germany, 53105