Status:
COMPLETED
Short Course Terlipressin for Control of Acute Variceal Bleeding
Lead Sponsor:
Aga Khan University
Collaborating Sponsors:
Ferozsons Laboratories Ltd.
Conditions:
Hemorrhage
Esophageal Varices
Eligibility:
All Genders
18-85 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether 24 hours of Terlipressin is as effective as 72 hours of Terlipressin in preventing re-bleed once esophageal variceal bleed has been controlled with en...
Detailed Description
The esophageal variceal bleeding is usually controlled with endoscopic treatment of variceal band ligation or sclerotherapy along with vasoactive drugs like Terlipressin or Octreotide. The risk of re-...
Eligibility Criteria
Inclusion
- Acute esophageal variceal bleed
- Liver cirrhosis
- Child's score \</= 11
Exclusion
- Patient on Mechanical ventilator and or ionotropic support
- Active angina, Recent Myocardial infarction or dynamic EKG changes
- Failure to control variceal bleed on initial endoscopy
- Gastric variceal bleed
- Spontaneous bacterial peritonitis at presentation
- Hepatocellular carcinoma or other liver metastatic malignancy
- Portal vein thrombosis
Key Trial Info
Start Date :
August 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2008
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT00369694
Start Date
August 1 2006
End Date
August 1 2008
Last Update
September 25 2008
Active Locations (1)
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1
The Aga Khan University Hospital
Karachi, Sindh, Pakistan, 74800