Status:

COMPLETED

Dose-Finding Study Of CP-675,206 And SU011248 In Patients With Metastatic Renal Cell Carcinoma

Lead Sponsor:

AstraZeneca

Conditions:

Carcinoma, Renal Cell

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

This study will determine the highest tolerable dose of CP-675,206 when given in combination with SU011248.

Eligibility Criteria

Inclusion

  • Histologically proven renal cell carcinoma with metastases
  • Eastern Cooperative Oncology Group (ECOG) PS of 0 or 1

Exclusion

  • Prior treatment with more than one systemic therapy for metastatic renal cell carcinoma
  • History of or known brain metastases, spinal cord compression or carcinomatous meningitis, or new evidence of brain or leptomeningeal disease on screening Computed Axial Tomography (CT) or Magnetic Resonance Imaging (MRI) scan

Key Trial Info

Start Date :

November 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2010

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT00372853

Start Date

November 1 2006

End Date

May 1 2010

Last Update

June 6 2012

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Research Site

Scottsdale, Arizona, United States, 85258

2

Research Site

New Brunswick, New Jersey, United States, 08903

3

Research Site

Cleveland, Ohio, United States, 44195

4

Research Site

Greenville, South Carolina, United States, 29605