Status:
COMPLETED
Preventing Depression Recurrence in Diabetes
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Major Depression
Diabetes
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
To study the effectiveness of sertraline (Zoloft) in treating depression in adults with diabetes. The study will also determine whether depressed diabetic patients who have successfully responded to s...
Detailed Description
Part A: Prevention of Depression Recurrence in Diabetes 1. To determine the efficacy of maintenance antidepressant medication in preventing or delaying recur-rence of major depression in diabetes. 2....
Eligibility Criteria
Inclusion
- 18-80
- Type 1 or Type 2 Diabetes
- Screen positive for depression
Exclusion
- Are pregnant or lactating
- Are known to be hypersensitive to the drug
- Have a recent history of myocardial infarction or unstable heart disease
- Have severe hepatic disease or renal impairment (serum creatinine \> 3 mg/dl)
- The subset of patients with psychiatric disorders thought to affect management (e.g., schizophrenia, alcohol and drug dependence) will also be excluded from participation
Key Trial Info
Start Date :
March 1 1998
Trial Type :
INTERVENTIONAL
End Date :
October 1 2004
Estimated Enrollment :
262 Patients enrolled
Trial Details
Trial ID
NCT00374426
Start Date
March 1 1998
End Date
October 1 2004
Last Update
March 2 2010
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110