Status:
COMPLETED
Treatment of Ulcerative Colitis With a Combination of Lactobacillus Rhamnosus and Lactobacillus Acidophilus.
Lead Sponsor:
Odense University Hospital
Collaborating Sponsors:
University of Southern Denmark
Crohn's and Colitis Foundation
Conditions:
Ulcerative Colitis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In this trial we test the hypothesis that a probiotic containing Lactobacillus acidophilus and Lactobacillus rhamnosus is an effective therapy for patients with ulcerative colitis.
Detailed Description
In the recent years there has been an increasing interest in the relationship between the gastrointestinal flora and gut function. Several studies have shown promising results for the use of probiotic...
Eligibility Criteria
Inclusion
- Patients with known ulcerative colitis
- At least one prior flare of the disease
- Clinically and endoscopically active disease
- Age: 18 and above
Exclusion
- Changes in azathioprine dosage within the last three months
- Patients with toxic megacolon, peritoneal reaction or severe colonic bleeding
- Known immunodeficiencies
- On-going infectious disease
- On-going treatment with NSAID or cholestyramine
- Pregnant og lactating women
Key Trial Info
Start Date :
February 1 2003
Trial Type :
INTERVENTIONAL
End Date :
May 1 2006
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT00374725
Start Date
February 1 2003
End Date
May 1 2006
Last Update
September 11 2006
Active Locations (2)
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1
Aarhus University Hospital
Aarhus, Denmark
2
Dept. of Medical Gastroenterology (afd.S), Odense University Hospital
Odense, Denmark, 5000 C