Status:

COMPLETED

Combined 18F-NaF/18F-FDG PET/MRI for Detection of Skeletal Metastases

Lead Sponsor:

Stanford University

Conditions:

Cancer

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This clinical trial studies the use of sodium fluorine-18 (18F-NaF) plus fluorine-18 (18F) fluorodeoxyglucose (FDG) positron emission tomography (PET)/ whole body magnetic resonance imaging (WBMRI) to...

Detailed Description

Eligible participants had previously received a bone scan using the radiolabel 99mTc-methyl diphosphonate (t99-MDP) as part of their regular medical care. 18F-NaF and 18F-FDG are radioactive substanc...

Eligibility Criteria

Inclusion

  • All patients were enrolled after receiving a regular medical care bone scan using the radiolabel 99mTc-methyl diphosphonate (t99-MDP).
  • INCLUSION CRITERIA
  • ≥ 18 years old at the time of the drug administration
  • ≥ Stage 3 breast cancer OR ≥ stage 2 prostate cancer OR prostate-specific antigen (PSA) \> 10 micrograms/L OR recurrent breast or prostate cancer
  • Capable of complying with study procedures
  • Able to remain still for duration of imaging procedure (about one hour)
  • Written informed consent
  • EXCLUSION CRITERIA
  • Pregnant or nursing
  • Metallic implants that contraindicate MRI
  • Renal function impairment that contraindicates MRI

Exclusion

    Key Trial Info

    Start Date :

    January 1 2006

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    March 14 2019

    Estimated Enrollment :

    114 Patients enrolled

    Trial Details

    Trial ID

    NCT00375830

    Start Date

    January 1 2006

    End Date

    March 14 2019

    Last Update

    December 12 2023

    Active Locations (1)

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    Stanford University School of Medicine

    Stanford, California, United States, 94305