Status:
TERMINATED
Prolonged Treatment for Infected Abortion After Hospital Discharge.
Lead Sponsor:
Hospital de Clinicas de Porto Alegre
Conditions:
Septic Abortion
Eligibility:
FEMALE
14-50 years
Phase:
PHASE4
Brief Summary
Patients with infected abortion will be treated with dilatation and curettage, intravenous antibiotics. The purpose of this study is to verify if it is necessary to keep the use of oral antibiotics af...
Detailed Description
The use of 7-10 days of treatment for infected/septic abortion is not based on clinical trials. A recent evidence showed that endometritis post cesarean section needs no treatment after hospital disch...
Eligibility Criteria
Inclusion
- History of intrauterine manipulation with contaminated objects.
- Vaginal secretion with fetid odor
- Presence of pus flowing through the cervical uterine
- Presence of peritonitis
- Leucocytosis (\> 14,000 leucocytes/mL)
- Vasodilatation, bounding pulse and paradoxically warm periphery with tachycardia (Heart rate\> 110 bpm)
- Cyanosis and/or paleness
- tachypnea(\> 30mpm)
- Arterial hypotension (SAP\< 90mmHg)
- Oliguria
- Fever (\> or = than 37,8°C)
Exclusion
- Refusal to participate in the project
- Prior use of antibiotics within one week
- Known allergy to Doxycycline or Metronidazole
- Presence of tubo-ovarian abscess
Key Trial Info
Start Date :
May 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT00376493
Start Date
May 1 2006
End Date
December 1 2007
Last Update
March 13 2008
Active Locations (1)
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1
Hospital de Clínicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil, 90035-003